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Drug test

NanoMIPs-based electrochemical sensors for selective detection of amphetamine

Illicit drugs consumption remains a public threat worldwide and represents a significant challenge for the local authorities. Of these, amphetamine (AMF) is a central nervous system stimulant but in the same time a FDA approved treatment of narcolepsy and ADHD. AMF represents the second most used stimulant drug in Europe, with 1.4 million young adults (15–34 years) consumers reported only in the last few year (1.4% of this age group).

The AMF can’t be directly detected using the electrochemical methods because it is not an electroactive compound. In this regard, electroactive molecularly imprinted nanoparticles (nanoMIPs) for AMF detection were synthesized and applied in a study carried out by, among others, the ‘Iuliu Hațieganu’ University of Medicine and Pharmacy Cluj-Napoca (UMF), the University of Leicester (ULEIC), and the University of Antwerp (UA), for the selective and sensitive detection of AMF.

As a result, a highly sensitive and portable electrochemical sensor based on molecularly imprinted nanoparticles (nanoMIPs) was developed.

Full article has been published in Microchemical Journal and can be found here.


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